| The role will include: |
As the Senior Chemist, you will help establish the synthetic labs, be responsible for its day to day running as well as ensuring a productive synthetic program to meet the catalogue and custom synthesis requirements. You will work closely with the management team.
| Tasks and Responsibilities of the Senior Chemists role: |
·
Design and develop chemistry for custom
synthesis projects.
This will typically be multi-step synthesis
producing chemical
entities ranging from of functionalised sugars,
nucleosides,
enzyme substrates, to oligosaccharides. The
scale of the
synthesis may range from milligrams to 100’s
grams.
·
Perform and manage the team’s synthetic
program making
catalogue carbohydrates and nucleosides
·
Route design of novel chemistries suitable
for scale up and
transfer from laboratory scale to kilo/plant
scale.
·
Carry out characterisation and data analysis
·
Record experimental detail and analytical
data accurately
·
Share basic maintenance and housekeeping
duties of laboratory
equipment and chemistry laboratory areas
All listed tasks and responsibilities are
deemed as essential functions to this
position; however, business conditions may
require reasonable accommodations for
additional task and responsibilities.
| Preferred Background for the role: |
·
PhD in synthetic organic chemistry,
preferably
in carbohydrate,
nucleoside or related research
·
Minimum 5 years experience in industry or
2-years postdoctoral
experience and min 3 years in industry
·
Familiarity with a wide range of synthetic
carbohydrate chemistry
is essential which may include:
glycosylation,
nucleosidations,
glucuronides, sugar sulfates and phosphates
·
Experience of conjugation chemistry of
carbohydrates for
example with proteins, lipids and biotins would
be an advantage
·
Familiarity with the HPLC purification,
experience on Agilent or
Varian HPLC system and LC-MS will be a plus
·
The successful candidate will be
self-motivated with a strong
desire to motivate and mentor your team with good
team-working
skills
·
Familiarity of commercial demands and the
need to delivery on
time and within specification
